Items tagged “nuclear medicine”
49 results found
Article
F-18 DOPA
F-18 DOPA (3,4-dihydroxy-6-[18F]fluoro-L-phenylalanine) is a PET radiotracer primarily used in the evaluation of neuropsychiatric diseases, movement disorders, and brain malignancies 1.
Production
L-DOPA is the nonproteinogenic amino acid precursor to dopamine with F-18 DOPA, in recent years,...
Article
Renal imaging in nuclear medicine
Renal imaging in nuclear medicine is a method to assess the kidneys and collecting systems via multiple different radioactive tracers.
Dynamic renal imaging is performed using Tc-99m MAG3 or Tc-99m DTPA, and static renal imaging is performed with Tc-99m DMSA. In addition, Tc-99m DTPA can be use...
Article
Tc99m mebrofenin
Tc99m-Mebrofenin: trimethyl bromo IDA, also known as TBIDA, or under the trade name Choletec, is a diagnostic radiopharmaceutical used in hepatobiliary imaging. It is one of the Tc99m IDA (iminodiacetic acid) analogs. It is taken up by hepatocytes through the same membrane transport mechanism as...
Article
Flip-flop fungus sign - FDG PET-CT
The flip-flop fungus sign suggests benign pulmonary disease on FDG-PET 1-4.
Lung cancer nodules demonstrate increasing FDG-avidity as the tumor grows. Lymph node spread occurs later and is therefore at an earlier stage of development and usually exhibits lower FDG-avidity 4.
Acutely, FDG-avidi...
Article
Iodine-131 iobenguane
Iodine-131 iobenguane, trade name Azedra, sometimes referred to as I-131 MIBG, is a theranostic (i.e. both therapeutic and diagnostic) agent used for the treatment of unresectable pheochromocytomas, paragangliomas, carcinoid, and neuroblastomas. It is created using the high specificity Ultratr...
Article
Lutetium-177 dotatate
Lutetium-177 dotatate, also known as Lu-177 oxodotreotide and by the trade name Lutathera (Novartis Pharmaceuticals Corporation, USA), is a theranostic agent approved as a second-line agent for the treatment of patients with inoperable and/or metastatic well-differentiated neuroendocrine tumors ...
Article
Lutetium-177 vipivotide tetraxetan
Lutetium-177 vipivotide tetraxetan, trade name Pluvicto, also known as 177Lu-PSMA-617, is a theranostic (i.e. both therapeutic and diagnostic) agent approved as a treatment for adult patients with treatment-resistant advanced metastatic prostate cancer. The treatment works by binding to cancer ...
Article
Radium-223 dichloride
Radium-223 dichloride, trade name Xofigo, is a radiopharmaceutical approved for the treatment of patients with symptomatic bone metastases and no visceral disease from prostate cancer resistant to anti androgen therapy. The molecule mimics calcium and forms a complex with hydroxyapatite at sites...
Article
Yttrium-90 ibritumomab tiuxetan
Yttrium-90 ibritumomab tiuxetan, also known by the trade name Zevalin (Acrotech Biopharma LLC, USA), is a theranostic radiopharmaceutical approved for the treatment of patients with relapsed or refractory low grade or follicular non-Hodgkin lymphoma (NHL). More specifically, it is a radioimmunot...