Items tagged “nuclear medicine”
60 results found
Superscan is intense symmetric activity in the bones with diminished renal and soft tissue activity on a Tc99m diphosphonate bone scan. Pathology This appearance can result from a range of etiological factors: diffuse metastatic disease prostatic carcinoma breast cancer transitional cell c...
Published 11 May 2010
Pelviureteric junction obstruction
Pelviureteric junction (PUJ) obstruction/stenosis, also known as ureteropelvic junction (UPJ) obstruction/stenosis, can be one of the causes of obstructive uropathy. It can be congenital or acquired with a congenital pelviureteric junction obstruction being one of the commonest causes of antenat...
Graves disease (also known as Basedow disease in mainland Europe 9) is an autoimmune thyroid disease and is the most common cause of thyrotoxicosis (up to 85%). Epidemiology There is a strong female predilection with an F:M ratio of at least 5:1. It typically presents in middle age. Clinical ...
Technetium agents based on the technetium-99m (Tc-99m) radioisotope are frequently used agents in medical imaging. A radiopharmaceutical labeled with Tc-99m constitutes a co-ordination complex in which ligands bond to a central atom of Tc-99m by co-ordinate covalent bonds 4 . The radioactive te...
Alzheimer disease (SPECT)
Published 29 Sep 2010
Calcaneal stress fracture
Published 20 Oct 2010
Radiopharmaceuticals are drugs that are bound to radioactive substances. The pharmaceutically active portion determines the activity that will be measured and the radioactive portion emits radiation that can be measured by the scanner. A number of radiopharmaceuticals are used in human imaging...
Tc-99m sulfur colloid
Technetium-99m sulfur colloid is one of the technetium radiopharmaceuticals. Characteristics photon energy: 140 keV physical half-life: 6 hours biological half-life normal distribution: liver: 85% spleen: 10% bone marrow: 5% excretion: hepatic target organ: liver, spleen pharmacokinet...
Xenon-133 is a radiopharmaceutical principally used when a performing VQ scan. Inhalation of this gas can also be used to assess cerebral blood flow. Mode of decay: Beta decay photon energy: 81 KeV physical half-life: 5.27 days biological half-life: 30 seconds normal distribution: lungs <1...
Iodine-123 (I123 or I-123) is a radioisotope of the element iodine (atomic number 53) used in nuclear medicine imaging including to scan the thyroid gland. Uses, dosages, and time of Imaging standard scan: 3.7-14.8 MBq (100-400 μCi) PO, image at 4-6 or 24 hours thyroid cancer scan: 55.5 MBq ...
Thyroid scan (I-123)
Thyroid scan (thyroid scintigraphy) is a nuclear medicine examination used to evaluate thyroid tissue. Clinical indications functional status of a thyroid nodule thyrotoxicosis: differential diagnosis thyroid cancer whole body scan for distant metastases estimation of local residual thyro...
Tc-99m DMSA (2,3 dimercaptosuccinic acid) is a technetium radiopharmaceutical used in renal imaging to evaluate renal structure and morphology, particularly in pediatric imaging for detection of scarring and pyelonephritis. DMSA is an ideal agent for assessment of the renal cortex as it binds to...
Tc-99m DTPA (diethylene-triamine-pentaacetate) is one of the technetium radiopharmaceuticals used in renal imaging and primarily used to measure the glomerular filtration rate (GFR). Characteristics photon energy: 140 KeV physical half-life: 6 hours biological half-life: 2.5 hours normal di...
Renal artery stenosis caused by aortic dissection
Published 25 Jul 2011
PET-CT is a combination of cross-sectional anatomic information provided by CT and the metabolic information provided by positron emission tomography (PET). PET is most commonly performed with 2-[F-18]fluoro-2-deoxy-D-glucose (FDG). Fluorine-18 (F-18) is an unstable radioisotope and has a half-...
Tc-99m MAG3 (mercaptoacetyltriglycine) is one of the technetium radiopharmaceuticals used in renal imaging. Due to favourable energy and dosimetric characteristics, MAG3 radiolabeled with technetium has replaced the iodide-131 Hippuran for the study of renal function (tubular secretion physiolog...
Tc-99m pertechnetate (Na+ 99mTc O4-) is one of the technetium radiopharmaceuticals used in imaging of thyroid, colon, bladder and stomach. Technetium (99mTc) has eight oxidation states 6, from -1 to +7; specifically, the oxidation state of technetium in the pertechnetate anion (99mTcO4-) is +7....
Thyroid scan (Tc-99m)
Tc-99m pertechnetate thyroid scan is a functional nuclear medicine study used to assess the thyroid gland. The uptake of the pertechnetate anion - similar in chemical-physical characteristics to the iodide ion - in the thyroid parenchyma is mediated by the NIS (Sodium-Iodide Symporter). However,...
Tc-99m HMPAO labeled WBC
Tc-99m HMPAO (hexamethylpropyleneamine oxime) labeled WBC is one of the technetium radiopharmaceuticals used in WBC imaging. There are three potential radiochemical impurities in the 99mTc-HMPAO: a hydrophilic secondary complex, the free pertechnetate and the reduced 99mTc-hydrolyzate. 1The min...