Items tagged “pancreas”

52 results found
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Acute pancreatitis

Acute pancreatitis (plural: pancreatitides) is an acute inflammation of the pancreas and potentially life-threatening. Terminology Two subtypes of acute pancreatitis are described in the Revised Atlanta Classification 1:  interstitial edematous pancreatitis the vast majority (90-95%) most o...
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Intraductal papillary mucinous neoplasm

Intraductal papillary mucinous neoplasms or tumors (IPMNs or IMPTs) are epithelial pancreatic cystic tumors of mucin-producing cells that arise from the pancreatic ducts. They are most commonly seen in elderly patients.  On imaging, particularly MRCP, they are characterized by single or multipl...
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Pancreatic ducts

The exocrine pancreas drains into the gastrointestinal tract via the main and accessory pancreatic ducts. Several anatomical variations of the typical ductal drainage pattern exist, reflecting variations in the embryological development and fusion of the dorsal and ventral pancreatic buds 13,14....
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Pancreatic neoplasms

There are numerous primary pancreatic neoplasms, in part due to the mixed endocrine and exocrine components. Classification Classification based on function exocrine: ~99% of all primary pancreatic neoplasms pancreatic ductal adenocarcinoma (commonly known as pancreatic cancer) 90-95%  acin...
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Pancreatoblastoma

Pancreatoblastomas are rare pediatric tumors of the pancreas. However, they are the most common pancreatic neoplasm of childhood and are often associated with a raised alpha-fetoprotein. Epidemiology There is slight male predilection. Usually occurs in the first decade of life with a mean age ...
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Pancreas

The pancreas (plural: pancreata) is an unpaired, mostly retroperitoneal organ that has endocrine and exocrine functions, with a role in glucose metabolism and digestion. Gross anatomy Location The pancreas is located at approximately the L1-L2 vertebral level in the anterior pararenal space o...
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Pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma, frequently referred to as pancreatic cancer, makes up the vast majority (~90%) of all pancreatic neoplasms and remains a disease with a very poor prognosis and high morbidity. Epidemiology Pancreatic cancer accounts for 22% of all deaths due to gastrointestina...
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Pancreatic pseudocyst

Pancreatic pseudocysts are common sequelae of acute pancreatitis or chronic pancreatitis, and the most common cystic lesion of the pancreas. They are important both in terms of management and differentiation from other cystic processes or masses in this region. Terminology The following are th...
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Autoimmune pancreatitis

Autoimmune pancreatitis is a form of chronic pancreatitis associated with autoimmune manifestations on clinical, histological, and laboratory grounds 1. Distinguishing this entity from other forms of chronic pancreatitis (such as alcohol-induced) is important as steroid treatment is effective b...
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Puestow procedure

The Puestow procedure or lateral pancreaticojejunostomy is a lateral side-to-side pancreaticojejunostomy that is used for the treatment of chronic pancreatitis. The pancreas is essentially filleted along its long axis from the uncinate process to the tail and connected to a Roux en-Y loop of je...
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Autoimmune pancreatitis (diagnostic criteria)

There are several sets of diagnostic criteria for autoimmune pancreatitis (AIP), with some overlap and contradictions. Several different sets of diagnostic criteria are in use 4. Asian 2008 AIP diagnostic criteria both criteria I to be fulfilled one criterion II consistent histology The cr...
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Pancreatic metastases

Pancreatic metastases are uncommon and are only found in a minority (3-12%) of patients with widespread metastatic disease at autopsy. They account for only 2-5% of all pancreatic malignancies. Epidemiology Demographics will match those of the primary tumor, but in general, will be in elderly ...
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Ranson criteria

Ranson criteria are useful in assessing prognosis in early acute pancreatitis. The more of the criteria are met the higher the mortality. Ranson criteria are assessed both at admission and at 48 hours. Criteria On admission age: >55 years white blood count: >16 000/mL blood glucose level: >...
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Serous cystadenoma of the pancreas

Serous cystadenoma of the pancreas, also referred as microcystic adenoma, is an uncommon type of benign cystic pancreatic neoplasm.  Epidemiology There is a recognized strong female predilection (M:F ~ 1:4) and usually presents in middle age to elderly patients (>60 years of age).  Associatio...
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Pancreatic lipomatosis

Pancreatic lipomatosis refers to fat accumulation in the pancreatic parenchyma. This finding is most often associated with obesity and aging. It tends to be the most common pathological condition involving the pancreas. The condition may occasionally simulate a mass-like lesion particularly when...
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Pancreatic trauma injury grading

A number of pancreatic injury grading systems have been proposed for pancreatic trauma. Classifications American Association for the Surgery of Trauma (AAST) 5,7 The proximal pancreas is defined as the gland to the right of the superior mesenteric vein (SMV)-portal vein axis whereas the dista...
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Paraduodenal pancreatitis

Paraduodenal pancreatitis is an uncommon type of focal chronic pancreatitis affecting the groove between the head of the pancreas, the duodenum and the common bile duct. Terminology The following entities with which it shares clinicopathological features are unified by this term and should no ...
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Chronic pancreatitis

Chronic pancreatitis represents the end result of a continuous, prolonged, inflammatory, and fibrosing process that affects the pancreas. This results in irreversible morphologic changes and permanent endocrine and exocrine pancreatic dysfunction. Epidemiology The most common cause of chronic ...
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Pancreatic neuroendocrine tumors

Pancreatic neuroendocrine tumors (pNET), also known as endocrine tumors of the pancreas, arise from pancreatic ductal stem cells and include some distinct tumors that match the cell type of origin.  Terminology Pancreatic neuroendocrine tumors have commonly been referred to as "islet cell tumo...
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Insulinoma

Insulinomas are the most common sporadic endocrine tumor of the pancreas. On imaging, they usually present as small well-defined hypervascular tumors that may be found anywhere in the pancreas.  Epidemiology Account for 40% of syndromic pancreatic endocrine tumors. The overall incidence is of...

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