Items tagged “toxicology”

7 results found

Sinusoidal obstruction syndrome

Sinusoidal obstruction syndrome (SOS), previously known as hepatic veno-occlusive disease (VOD), is a condition arising from occlusion of hepatic venules. Clinical presentation right upper quadrant pain painful hepatomegaly ascites abnormal liver function tests Pathology Toxic injury to l...

Nitrous oxide toxicity

Nitrous oxide (N2O) toxicity has serious medical sequelae affecting both the CNS and the bone marrow. Neurological effects include encephalopathy, myelopathy, and neuropathy. This results from demyelination and gliosis due to a functional deficiency of vitamin B12 1. Bone marrow toxicity may lea...

Metronidazole central nervous system toxicity

Metronidazole, which is used to treat a wide variety of bacterial and protozoal infections can, in exceedingly rare cases, lead to central nervous system toxicity. Epidemiology Affected patients range widely in age, with the peak incidence occurring in the fifth and sixth decades. Hepatic dise...

Methanol poisoning

Methanol poisoning is a cause of an acute toxic leukoencephalopathy that also has eventual chronic sequelae.  Epidemiology Methanol is found in a variety of consumer products including perfumes, model aircraft and car fuels, windshield washing solutions, carburator cleaners, solid cooking fuel...

Heavy metals

Heavy metals is a vague term referring to metals of toxicologic significance. While historically this referred to metals of a high density/mass, such as those in the lanthanides and actinides (on the periodic table), it now encompasses a broad array of elements, including some metalloids (e.g. a...


Cobalt (chemical symbol Co) is an essential trace element. Its most important function in humans is as the active metal atomic center of vitamin B12. Chemistry Basic chemistry Cobalt is a shiny grey-silvery transition metal with an atomic number 27 and an atomic weight of 58.93 Daltons (Da). ...

Acute exogenous lipoid pneumonia

Acute exogenous lipoid pneumonia is an uncommon form of exogenous lipoid pneumonia and is typically caused by the aerosolization and aspiration of a highly viscous hydrocarbon, such as vegetable oil, mineral oil or petroleum jelly 5. The more common pulmonary toxicity exerted by hydrocarbons is ...

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