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Malignant transformation

Last revised by Mohammad Taghi Niknejad on 17 Jan 2023

Citation, DOI, disclosures and article data

Citation:

Bell D, Niknejad M, Malignant transformation. Reference article, Radiopaedia.org (Accessed on 20 May 2024) https://doi.org/10.53347/rID-61898

DOI:

https://doi.org/10.53347/rID-61898

Permalink:

https://radiopaedia.org/articles/61898

rID:

61898

Article created:

23 Jul 2018, Daniel J Bell ◉

Disclosures:

At the time the article was created Daniel J Bell had no recorded disclosures.

View Daniel J Bell's current disclosures

Last revised:

17 Jan 2023, Mohammad Taghi Niknejad ◉

Disclosures:

At the time the article was last revised Mohammad Taghi Niknejad had no financial relationships to ineligible companies to disclose.

View Mohammad Taghi Niknejad's current disclosures

Revisions:

4 times, by 2 contributors - see full revision history and disclosures

Systems:

Oncology

Sections:

Pathology

Synonyms:

Transformation to cancer
Cancer transformation
Malignancy transformation
Malignancy progression
Malignant progression

Malignant transformation is the term given to the process whereby either normal, metaplastic, or benign neoplastic tissue, becomes a cancer. The process usually occurs in a series of steps and the affected tissue gradually accumulates the genetic mutations that express a malignant phenotype. The genetic steps are gradually being elucidated ¹.