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Articles

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13 results found
Article

Lugano classification (response to treatment on CT)

The Lugano classification is a lymphoma staging system resulting from recommended changes in 2011 to the Ann Arbor staging with Cotswolds modifications. This article outlines the classification's response to treatment based on CT.  Also included in the classification are staging and response to...
Article

WHO classification of haematolymphoid tumors

The World Health Organization (WHO) classification of haematolymphoid tumors is the most widely used pathologic classification system for hematopoietic and lymphoid neoplasms. The current revision 1, known as the 5th edition, was published in 2022 and supersedes the 4th edition revised published...
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Lugano staging classification

The Lugano staging classification is the lymphoma staging system that is most commonly used in clinical practice currently. The categories for initial staging are defined in this article. See separate articles for the Lugano criteria for response assessment by PET-CT or by CT alone, as well as g...
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Non-Hodgkin lymphoma

Non-Hodgkin lymphoma (NHL) is a neoplasm of the lymphoid tissues originating from B cell precursors, mature B cells, T cell precursors, and mature T cells. It includes all types of lymphomas apart from Hodgkin lymphoma. See the WHO classification of haematolymphoid tumors for further informatio...
Article

Lugano classification (PET-CT treatment response)

The Lugano classification is a lymphoma staging system for non-Hodgkin and Hodgkin lymphoma. This article outlines the classification's response to treatment based on PET-CT.  Also included in the classification are staging and response to treatment based on CT. Scoring system The Lugano clas...
Article

Hypersensitivity reaction

Hypersensitivity reactions are the immunological response to both exogenous and endogenous antigens, and form the basis for many diseases.  Pathology Classification Using the Gell and Coombs' classification, there are four types of hypersensitivity reactions, each mediated by a different mech...
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Lymphoma response to immunomodulatory therapy criteria (LYRIC)

The Lymphoma Response to Immunomodulatory Therapy Criteria (LYRIC) represents an adaptation of the Lugano classification for the evaluation of lymphoma after immune-based treatment. During immunomodulatory agents (e.g. checkpoint inhibitors) therapy, imaging findings suggestive of progressive d...
Article

Myeloproliferative neoplasm

Myeloproliferative neoplasms are a diverse group of conditions that are characterized by an excess of terminally differentiated myeloid cells (red cells, white cells, and/or platelets) in the peripheral blood. Under WHO classification of haematolymphoid tumors, myeloproliferative neoplasms are c...
Article

Histiocyte Society classification of histiocytoses

The Histiocyte Society classification of histiocytoses and neoplasms of macrophage-dendritic cell lineages is currently in its 2016 revision of the organization's initial classification system from 1987. Terminology Histiocytes are mononuclear phagocytes that reside in tissues, including macro...
Article

Lugano classification (lesion measurement guidelines)

The Lugano classification is a lymphoma staging system resulting from recommended changes in 2011 to the Cotswolds modified Ann Arbor staging. This article outlines the lesion measurement guidelines for the system: Eligible lesions lymph nodes: the longest diameter in axial plane should be >1....
Article

Disseminated histoplasmosis

Disseminated histoplasmosis, also known as progressive disseminated histoplasmosis, is a severe form of histoplasmosis infection typically seen in immunosuppressed patients, especially in the setting of HIV infection. It results from hematogenous dissemination of the infection, involving multipl...
Article

Bone lymphoma

Lymphoma of the bone may represent lymphoma that has originated within that bone itself i.e. primary, or metastasized there from another organ/tissue, i.e. secondary. Secondary forms of bone lymphoma are much more common than the primary bone form. primary osseous lymphoma secondary osseous ly...
Article

Ann Arbor staging system (historical)

The Ann Arbor staging system was the landmark lymphoma staging classification system for both Hodgkin lymphoma and non-Hodgkin lymphoma. It is named after the town of Ann Arbor in the US state of Michigan where the Committee on Hodgkin's Disease Staging Classification met in 1971 to agree on it....

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