Articles
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74 results found
Article
Lemierre syndrome
Lemierre syndrome (also known as postanginal septicemia) refers to thrombophlebitis of the internal jugular vein(s) with distant metastatic anaerobic septicemia in the setting of initial bacterial oropharyngeal infection such as pharyngitis/tonsillitis into lateral pharyngeal spaces of the neck ...
Article
Doege-Potter syndrome
Doege-Potter syndrome is a paraneoplastic non-islet cell tumor hypoglycemia, secondary to a solitary fibrous tumor, most commonly pulmonary, secreting insulin-like growth factor-2 (IGF-2).
It is rare and more often found with higher grade solitary fibrous tumors 1-4.
Article
Superior vena cava obstruction
Superior vena cava obstruction (SVCO) can occur from extrinsic compression, intrinsic stenosis, or thrombosis of the superior vena cava. Malignancies are the main cause and are considered an oncologic emergency. Superior vena cava syndrome (SVCS) refers to the clinical syndrome with symptoms tha...
Article
Thoracic outlet syndrome
Thoracic outlet syndrome refers to a group of clinical syndromes caused by congenital or acquired compression of the brachial plexus or subclavian vessels as they pass through the superior thoracic aperture 11.
Clinical presentation
Clinical presentation will depend on the structure compresse...
Article
Lady Windermere syndrome
Lady Windermere syndrome refers to a pattern of pulmonary Mycobacterium avium complex (MAC) infection seen typically in elderly white women who chronically suppress the normal cough reflex. A fastidious nature and a reticence to expectorate are believed to predispose such persons to infections w...
Article
Yellow nail syndrome
The yellow nail syndrome (YNS) is a rare disorder principally affecting the lymphatic system.
It is characterized by a clinical triad:
nail discolouration (chromonychia): yellow to dark green slow-growing dystrophic nails (scleronychia) 9
lymphedema (peripheral/primary)
pulmonary disease: se...
Article
VEXAS syndrome
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a severe, treatment-refractory, monogenic, multiorgan, autoinflammatory condition with vasculitic and hematological complications.
Epidemiology
VEXAS syndrome is likely to be rare, but also likely to be underdiagnosed...
Article
Rosai-Dorfman disease
Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy or Rosai-Dorfman-Destombes disease, is a rare benign idiopathic proliferative disease that involves phagocytic histiocytes.
Epidemiology
The disease predominantly occurs in young adults with a mean age at pre...
Article
Acute coronary syndrome
Acute coronary syndrome (ACS) is a group of cardiac diagnoses along a spectrum of severity due to the interruption of coronary blood flow to the myocardium, which in decreasing severity are:
ST elevation myocardial infarction (STEMI)
non-ST elevation myocardial infarction (NSTEMI)
unstable an...
Article
Hyperimmunoglobulin IgE syndrome
Hyperimmunoglobulin E (hyper IgE) syndrome (HIES), also known as Job syndrome, consists of a heterogeneous group of complex hereditary combined B- and T-cell immune deficiency diseases characterized by recurrent Staphylococcus aureus chest infections, characteristic coarse facial appearance and ...
Article
Shrinking lung syndrome
Shrinking lung syndrome refers to a rare thoracic complication of systemic lupus erythematosus (SLE) characterized by:
unexplained dyspnea
restrictive pattern on pulmonary function tests
elevated hemidiaphragm
Epidemiology
As with SLE in general, it is thought to carry a increased female pr...
Article
Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a clinical syndrome and considered the most common and the most lethal form of pulmonary fibrosis corresponding to the histologic and imaging pattern of usual interstitial pneumonia. It is more common in elderly men and diagnosed by:
histological or imagi...
Article
Middle East respiratory syndrome coronavirus (MERS-CoV) infection
Middle East respiratory syndrome coronavirus (MERS-CoV) infection is an uncommon coronavirus infection (<1000 cases) with the first case reported in Saudi Arabia in 2012. It most commonly causes pneumonia and acute renal failure with a mortality rate of ~40%. MERS-CoV raises concern because of i...
Article
Platypnoea-orthodeoxia syndrome
Platypnoea-orthodeoxia syndrome refers to the concomitant occurrence of dyspnea and hypoxemia, respectively, which are precipitated by assuming an upright position and alleviated by assuming a recumbent position 4.
Clinical presentation
As the name of the syndrome suggests, the hallmark clinic...
Article
Cerebral hypoventilation syndrome
Cerebral hypoventilation syndrome refers to a congenital condition characterized by hypoventilation during sleep with no other abnormalities of the cardiorespiratory system. There is a decrease in the depth of breathing.
It is also known as central sleep apnea, congenital central hypoventilatio...
Article
Congenital high airway obstruction syndrome
Congenital high airway obstruction syndrome or sequence (CHAOS) refers to a rare, often lethal, congenital laryngotracheal condition and is primarily characterized by obstruction to the fetal upper airway.
Epidemiology
Associations
Fraser syndrome
Pathology
CHAOS can be of three possible ty...
Article
Non-steroidal anti-inflammatory drug exacerbated respiratory disease
Non-steroidal anti-inflammatory drug (NSAID) exacerbated respiratory disease refers to the clinical constellation of 1,2:
hypersensitivity to aspirin (and other NSAIDs)
nasal polyposis / rhinosinusitis
asthma
Terminology
Non-steroidal anti-inflammatory drug (NSAID) exacerbated respiratory d...
Article
Tietze syndrome
Tietze syndrome is a benign condition characterized by a self-limiting inflammation of the costal cartilages often with hypertrophy. Although often described as such, it is not a costochondritis 9.
Epidemiology
The exact incidence of occurrence is not known. It is seen most commonly in the 2nd...
Article
Neurofibromatosis type 1 (thoracic manifestations)
Thoracic manifestations of neurofibromatosis type 1 (NF1), or von Recklinghausen disease, are related to pulmonary and mediastinal features of this multisystem neurocutaneous disorder, which is the most common phakomatosis.
For thoracic manifestations involving the skeleton, such as focal thora...
Article
Drug rash with eosinophilia and systemic symptoms syndrome
The drug rash with eosinophilia and systemic symptoms (DRESS) syndrome typically manifests as a skin rash, fever, lymph nodal enlargement with variable internal organ involvement, and represents a hypersensitivity reaction to medication.
Clinical presentation
Clinical presentation can be vari...