Carney triad
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The Carney triad is a rare syndrome defined by the coexistence of three tumours:
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extra-adrenal paraganglioma (e.g. spinal paraganglioma)
- initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal paragangliomas 1
- gastric gastrointestinal stromal tumours (GIST)
- pulmonary chondroma
In most cases, only 2 of the 3 tumours are present at the time of diagnosis. It typically affects young people.
Terminology
It is not to be confused with the related Carney-Stratakis syndrome, or the unrelated Carney complex
History and etymology
First described by J Aidan Carney, an American professor of pathology, and colleagues in 1977 5.
-<p>The <strong>Carney triad</strong> is a rare syndrome defined by the coexistence of three tumours:</p><ul>- +<p><strong>Carney triad</strong> is a rare syndrome defined by the coexistence of three tumours:</p><ul>
-<a href="/articles/extra-adrenal-paraganglioma">extra-adrenal paraganglioma </a>(e.g. <a href="/articles/spinal-paraganglioma">spinal paraganglioma</a>)<ul><li>initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal <a href="/articles/paraganglioma-1">paragangliomas</a> <sup>1</sup>- +<a href="/articles/paraganglioma-1">extra-adrenal paraganglioma</a> (e.g. <a href="/articles/spinal-paraganglioma">spinal paraganglioma</a>)<ul><li>initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal <a href="/articles/paraganglioma-1">paragangliomas</a> <sup>1</sup>
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