Diffuse anoxic brain injury post cardiac arrest

Discussion:

The MR findings and clinical course are somewhat unusual. 

The initial period of normality followed by neurological deficit and white matter abnormalities suggested delayed posthypoxic leukoencephalopathy however the very short interval between initial insult and severity of neurological dysfunction are atypical. 

The alternative diagnosis is that of diffuse anoxic brain injury which can, albeit less frequently than grey matter, affect the white matter diffusely. As such this diagnosis is favored. 

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