Atypical meningioma - grade 2
The patient went on to have a resection.
Histology
Sections show a meningeal base tumor which is attached to the dura. The tumor consists of ahypercellular tumor which has sheet-like growth pattern with large nodules separated by fibrous bands. Thetumour cells have oval nuclei with small nucleoli. No significant nuclear pleomorphism is seen. The cellshave a small amount of eosinophilic cytoplasm. The tumor has increased cellularity with areas of sheet-likegrowth pattern. Areas with small cell-like change are present. Mitotic figures are not conspicuous up to 2 mitoses per 10 high power field are seen. Immunohistochemistry shows tumor stains strongly positive with SSTR2 and negative for STAT6.
Bone flap: Decalcified sections show bone with focal fibroblastic tissue. No tumor identified
Final diagnosis:
Atypical meningioma WHO grade 2