Choroid plexus
Citation, DOI, disclosures and article data
At the time the article was created Margaret Nguyen had no recorded disclosures.
View Margaret Nguyen's current disclosuresAt the time the article was last revised Tariq Walizai had no financial relationships to ineligible companies to disclose.
View Tariq Walizai's current disclosuresThe choroid plexus is located within the cerebral ventricles and is made of choroidal epithelial cells (type of ependymal cell), loose connective tissue (tela choroidea), and permeable capillaries. It produces cerebrospinal fluid.
The choroid plexuses also form the blood-CSF barrier alongside arachnoid and arachnoid villi 2.
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Gross anatomy
Location
the roof of the temporal horns of the lateral ventricles, extending along the floor of the body of the lateral ventricles, through the interventricular foramen of Monro, and along the roof of the third ventricle. They typically do not extend into the frontal or occipital horns of the lateral ventricles
the medullary part of the fourth ventricle, extending into the lateral apertures (of Luschka)
Radiographic features
CT and MRI
Rich in blood supply and lack of blood-brain barrier lead to avid enhancement of a normal choroid plexus after contrast administration. However, the enhancement may appear asymmetrical on both sides of the brain or mass-like, leading to false interpretations of tumour 4.
On the other hand, choroid plexus can be entirely calcified and lack enhancement which can resemble other types of non-enhancing tumours such as tuberculoma, neurocysticercorsis, non-enhancing meningioma or schwannoma 4.
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Related pathology
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vascular
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infection and inflammation
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neoplastic
References
- 1. Strazielle N & Ghersi-Egea J. Choroid Plexus in the Central Nervous System: Biology and Physiopathology. J Neuropathol Exp Neurol. 2000;59(7):561-74. doi:10.1093/jnen/59.7.561 - Pubmed
- 2. Liddelow S. Development of the Choroid Plexus and Blood-CSF Barrier. Front Neurosci. 2015;9:32. doi:10.3389/fnins.2015.00032 - Pubmed
- 3. Last RJ, McMinn RMH. Last's Anatomy Regional and Applied. 9th ed. New York: Churchill Livingstone; 2003. p. 589-590.
- 4. McKinney A. Choroid Plexus: Normal Locations and Appearances. Atlas of Normal Imaging Variations of the Brain, Skull, and Craniocervical Vasculature. 2017;:177-237. doi:10.1007/978-3-319-39790-0_11
Incoming Links
- Choroidal epithelial cells
- Medial posterior choroidal artery
- Haemochromatosis (CNS manifestations)
- Atypical choroid plexus papilloma
- Germinal matrix haemorrhage
- Cerebrospinal fluid
- Ventricular system
- Lateral ventricle
- Ventriculitis
- Cerebellopontine angle mass
- Head ultrasound
- Choroid plexus hyperplasia
- Internal cerebral vein
- Ependymal cells
- Caudothalamic groove
- Transcranial Doppler sonography (ultrasound)
- Hydranencephaly
- Transthyretin amyloidosis
- Pia mater
- Langerhans cell histiocytosis (CNS manifestations)
- Choroid plexus xanthogranulomata
- Choroid plexus lipoma
- Bilateral choroid plexus xanthogranuloma
- Intracranial ventricular anatomy
- Benign miliary osteoma cutis
- Choroid plexus xanthogranulomas
- Bochdalek's flower basket
- Atypical choroid plexus papilloma
- Choroid plexus carcinoma
- Tela choroidea and choroid plexus of lateral ventricles (Gray's illustration)
- Choroid plexus cyst
- Choroid plexus xanthogranuloma
- Choroid plexus xanthogranuloma
- Large choroid plexus xanthogranuloma
- Choroid plexus xanthogranuloma
- Aicardi syndrome
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