Intercostobrachial nerve

Last revised by Joachim Feger on 4 Feb 2025

The intercostobrachial nerve is a lateral cutaneous branch of the second intercostal nerve that supplies sensation to the skin of the axilla. It leaves the second intercostal space at the midaxillary line and subsequently pierces the serratus anterior muscle to enter the subcutaneous tissues of the axilla 1-3.

  • the lateral cutaneous branch of the third intercostal nerve may give rise to a second intercostobrachial nerve

  • the intercostobrachial nerve may join the medial cutaneous nerve of the arm to supply the skin of the medial arm

The nerve may be injured during axillary surgery such as nodal clearance for breast cancer 1. Preservation of the nerve is usually preferred and attempted during axillary dissection for breast cancer. It is a sensory nerve and supplies the skin over the second intercostal space and the medial upper arm and forearm. This reduces the sensory deficit postoperatively 4.

Given it supplies the skin of the axilla, it is sometimes referred to as the 'tickle' nerve.

Cases and figures

  • Figure 1: intercostal nerves (Gray's illustrations)
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