Intramembranous ossification
Citation, DOI, disclosures and article data
Citation:
Mayhew P, Knipe H, Thurston M, et al. Intramembranous ossification. Reference article, Radiopaedia.org (Accessed on 16 Mar 2025) https://doi.org/10.53347/rID-44008
rID:
44008
Article created:
2 Apr 2016,
Pamela Mayhew
Disclosures:
At the time the article was created Pamela Mayhew had no recorded disclosures.
View Pamela Mayhew's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Henry Knipe had no recorded disclosures.
View Henry Knipe's current disclosures
Revisions:
7 times, by
7 contributors -
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Intramembranous ossification describes the process of ossification from mesenchymal cells (stem cells) without a cartilaginous template and is involved in the healing process of fractures. The stages of intramembranous ossification osteogenesis are as follows:
- mesenchymal cells differentiate into osteoblasts
- osteoblasts deposit matrix which becomes mineralized
- immature woven trabeculae (primary spongiosa) is deposited
- primary spongiosa is replaced by secondary bone
- bone marrow formation
- primary cortical bone
Gross anatomy
Seen in the formation of:
References
- 1. Resnick D, Kransdorf M. Bone and joint imaging. Saunders. ISBN:0721602703. Read it at Google Books - Find it at Amazon
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