Intraparotid nodal metastases
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Intra-parotid nodal metastases refer to metastatic involvement of intraparotid lymph nodes from either a primary parotid tumour or an extra-parotid tumour in the head an neck (e.g. nasopharyngeal carcinoma)
Location
There may be a predilection towards the superficial lobe or tail region3
Prognostic significance
The
- the presence of intra-parotid metastatic nodal involvement in those with a known head and neck skin squamous cell carcinoma could imply occult cervical nodal involvement 2.
- the presence of intra-parotid metastatic nodal involvement in those with a known primary parotid cancer can be strongly associated with a worse disease-specific survival and a higher risk of locoregional recurrence 4.
-<p><strong>Intra-parotid nodal metastases</strong> refer to metastatic involvement of <a title="Intraparotid lymph nodes" href="/articles/intraparotid-lymph-nodes-2">intraparotid lymph nodes</a> from either a primary parotid tumour or an extra-parotid tumour in the head an neck (e.g. <a title="Nasopharyngeal carcinoma" href="/articles/nasopharyngeal-carcinoma">nasopharyngeal carcinoma</a>)</p><h5>Location</h5><p>There may be predilection towards the superficial lobe or tail region </p><h4>Prognostic significance</h4><p>The presence of intra-parotid metastatic nodal involvement in those with a </p>- +<p><strong>Intra-parotid nodal metastases</strong> refer to metastatic involvement of <a href="/articles/intraparotid-lymph-nodes-2">intraparotid lymph nodes</a> from either a primary parotid tumour or an extra-parotid tumour in the head an neck (e.g. <a href="/articles/nasopharyngeal-carcinoma">nasopharyngeal carcinoma</a>)</p><h5>Location</h5><p>There may be a predilection towards the superficial lobe or tail region <sup>3</sup></p><h4>Prognostic significance</h4><ul>
- +<li>the presence of intra-parotid metastatic nodal involvement in those with a known head and neck skin squamous cell carcinoma could imply occult cervical nodal involvement <sup>2</sup>.</li>
- +<li>the presence of intra-parotid metastatic nodal involvement in those with a known primary parotid cancer can be strongly associated with a worse disease-specific survival and a higher risk of locoregional recurrence<sup> 4</sup>.</li>
- +</ul>
References changed:
- 1. Feng Y, Liu F, Cheng G, Fang Q, Niu X, He W. Significance of Intraparotid Node Metastasis in Predicting Local Control in Primary Parotid Cancer. Laryngoscope. 2019;129(10):2309-12. <a href="https://doi.org/10.1002/lary.27701">doi:10.1002/lary.27701</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/30549298">Pubmed</a>
- 2. Dür C, Salmina C, Borner U, Giger R, Nisa L. Relevance of Intraparotid Metastases in Head and Neck Skin Squamous Cell Carcinoma. Laryngoscope. 2021;131(4):788-93. <a href="https://doi.org/10.1002/lary.28985">doi:10.1002/lary.28985</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/32918494">Pubmed</a>
- 3. Kashiwagi N, Murakami T, Toguchi M et al. Metastases to the Parotid Nodes: CT and MR Imaging Findings. Dentomaxillofac Radiol. 2016;45(8):20160201. <a href="https://doi.org/10.1259/dmfr.20160201">doi:10.1259/dmfr.20160201</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/27635667">Pubmed</a>
- 4. Lim C, Gilbert M, Johnson J, Kim S. Clinical Significance of Intraparotid Lymph Node Metastasis in Primary Parotid Cancer. Head Neck. 2014;36(11):1634-7. <a href="https://doi.org/10.1002/hed.23507">doi:10.1002/hed.23507</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/24123567">Pubmed</a>
- 5. Guntinas-Lichius O, Thielker J, Robbins K et al. Prognostic Role of Intraparotid Lymph Node Metastasis in Primary Parotid Cancer: Systematic Review. Head Neck. 2021;43(3):997-1008. <a href="https://doi.org/10.1002/hed.26541">doi:10.1002/hed.26541</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/33169420">Pubmed</a>
Systems changed:
- Head & Neck
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Parotid nodal metastasis
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Metastases to parotid nodes
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