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Citation:
Radswiki T, Skandhan A, Tatco V, et al. Malignant mixed germ cell tumor of the ovary. Reference article, Radiopaedia.org (Accessed on 17 Mar 2025) https://doi.org/10.53347/rID-15193
A malignant mixed germ cell tumor of the ovary is a subtype of ovarian germ cell tumor. These are not to be confused with malignant mixed Müllerian tumors of the ovary.
These tumors are rare. They most commonly affect adolescent women of reproductive age 1.
They are made up of mixed germ cell constituents. Ovarian dysgerminoma is a constituent in the majority of cases, and the mixed germ cell tumors can be subdivided into dysgerminomatous and nondygerminomatous tumors.
The most common components of nondysgerminomatous tumors are yolk sac and immature teratoma. Mixed germ cell tumors with embryonal carcinoma, nongestational choriocarcinoma, and polyembryoma components are less common.
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1. Moniaga NC, Randall LM. Malignant mixed ovarian germ cell tumor with embryonal component. J Pediatr Adolesc Gynecol. 2011;24 (1): e1-3. doi:10.1016/j.jpag.2010.05.001 - Pubmed citation
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2. Kurman RJ, Norris HJ. Malignant mixed germ cell tumors of the ovary. A clinical and pathologic analysis of 30 cases. Obstet Gynecol. 1976;48 (5): 579-89. - Pubmed citation
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3. 5. Nucci MR, Oliva E. Gynecologic Pathology. Churchill Livingstone. (2009) ISBN:0443069204. Read it at Google Books - Find it at Amazon
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