Common causes of polyostotic bone lesions in adults include:
- inflammatory
- arthritic or synovial-based lesions
- neoplastic
- benign
- non-ossifying fibromas (fibroxanthomas)
- polyostotic fibrous dysplasia (McCune-Albright syndrome)
- malignant
- benign
- metabolic
- infection
-
osteomyelitis
- bacterial
- tuberculous
- fungal
- smallpox residual
-
osteomyelitis
- others
- Paget disease
- bone infarcts and aseptic necrosis
- trauma
- fractures
- dislocations
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