Posterior pituitary

Last revised by Frank Gaillard on 6 Mar 2025

The posterior pituitary (also known as neurohypophysis) is a direct extension from the hypothalamus and does not synthesise any hormones, but rather releases oxytocin and ADH (vasopressin) which has travelled down the infundibulum in vesicles termed Herring bodies. The cell bodies reside into hypothalamic nuclei: 

The infundibular stalk is also considered part of the neurohypophysis and extends from the tuber cinereum and pierces the diaphragma sellae before being surrounded by the pars tuberalis of the anterior pituitary.  

Radiographic features

MRI

In the majority of normal studies, the posterior pituitary gland is visible as a region of T1 hyperintensity (posterior pituitary bright spot), due to T1 shortening from vasopressin content. It is not always visible. The prevalence varies according to different studies, ranging from 52% to over 90% 5.

Following the administration of contrast, it enhances vividly 4.

For relations and blood supply, please see the main pituitary gland article here.

Related pathology

Cases and figures

  • Figure 1: posterior pituitary
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