Citation, DOI, disclosures and article data
Citation:
Skandhan A, Hacking C, Bell D, et al. Spontaneous retroperitoneal hemorrhage. Reference article, Radiopaedia.org (Accessed on 21 Mar 2025) https://doi.org/10.53347/rID-25596
Disclosures:
At the time the article was last revised Craig Hacking had the following disclosures:
- Philips Australia, Paid speaker at Philips Spectral CT events (ongoing)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Craig Hacking's current disclosures
Spontaneous retroperitoneal hemorrhage (SRH) is a distinctive clinical pathology of retroperitoneal bleeding without a preceding history of trauma.
For a broader discussion, including other etiologies, please refer to the parental article on retroperitoneal hemorrhage.
Clinical presentation may be vague and varied:
- no inciting history
- no evidence of cutaneous bruising
- back, lower abdominal or groin pain
- hemodynamic instability
- fall in hemoglobin
The pathophysiology and pathogenesis of spontaneous retroperitoneal bleeding are unclear. Many hypotheses have been put forth:
- diffuse vasculopathy and arteriosclerosis of small retroperitoneal vessels renders them friable and prone to rupture 1
- anticoagulation induced immune microangiopathy may cause an unrecognised minor trauma in the microcirculation to cause a hemorrhage 2
Etiology
Spontaneous retroperitoneal hemorrhage is uncommon and is almost exclusively seen in association with:
- rupture of aortic or visceral artery aneurysm
- rupture of a pathological lesion in a retroperitoneal organ (renal and adrenal)
- anticoagulation states
- coagulopathies
- hemodialysis
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Treatment and prognosis
Based on the clinical scenario and cause, the management can be endovascular repair or open surgery.
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1. Davies GA, Lazo-Langner A, Shkrum M et-al. Spontaneous retroperitoneal hemorrhage in a patient with prolymphocytic transformation of chronic lymphocytic leukemia. Case Rep Hematol. 2013;2013: 802376. doi:10.1155/2013/802376 - Free text at pubmed - Pubmed citation
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2. McCort JJ. Intraperitoneal and retroperitoneal hemorrhage. Radiol. Clin. North Am. 1977;14 (3): 391-405. Pubmed citation
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3. Jarral OA, Todd C, Willson PD. Hemorrhagic shock secondary to spontaneous rupture of a non-secretory adrenal cortical tumour: A case report. Can Urol Assoc J. 2011;4 (6): E161-3. Free text at pubmed - Pubmed citation
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4. Sunga KL, Bellolio MF, Gilmore RM et-al. Spontaneous retroperitoneal hematoma: etiology, characteristics, management, and outcome. J Emerg Med. 2012;43 (2): e157-61. doi:10.1016/j.jemermed.2011.06.006 - Pubmed citation
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