Giant renal angiomyolipoma

Discussion:

Patient underwent left renal angiogram with embolization, followed by left nephrectomy with pathology results proving the mass to represent a giant angiomyolipoma.

Key points:

  • most common benign tumor of the kidney

  • 95% contain macroscopic fat, virtually diagnostic for AML (if calcifications are present, it could be an RCC)

  • associated with tuberous sclerosis, where they can be bilateral

  • if greater than 4 cm, portray a higher risk of bleeding and intervention may be necessary

  • 5% are lipid poor (no macroscopic fat)

  • don't confuse microscopic with macroscopic fat. Drop of signal on out-of-phase imaging suggests intracellular or microscopic fat, a feature that can be seen not uncommonly with clear cell carcinoma

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