Gastrointestinal stromal tumour of stomach

Discussion:

The patient underwent gastric mass resection, and histopathology with IHC evaluation confirmed a gastrointestinal stromal tumour without evidence of malignancy transformation.

The stomach is the most common site for GIST, followed by the small intestine, colon, rectum, and oesophagus. Most GISTs are benign; however, in the case of large exophytic masses more than 5 cm in diameter, heterogeneous enhancement due to central degeneration, ulceration, and local invasion should be considered malignant transformation.

Regional and metastatic lymphadenopathy are not common in the malignant GISTs, and the liver is the most common site for metastasis.

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