Spondylodiscitis most commonly affects the lumbar spine. It can progress to psoas abscess formation and residual deformity. MRI is the modality of choice for reliable diagnosis and for differentiation from similar diseases. Important diagnostic signs include a T2 hyperintense signal at the intervertebral disc, endplate erosions, epidural and psoas abscesses, and enhancement of the disc, endplates, and the involved perivertebral soft tissues.