Glioblastoma NOS

Discussion:

This case illustrates the typical appearance of high-grade glioma. The patient went on to have surgery and the diagnosis was confirmed. 

Histology

MICROSCOPIC DESCRIPTION: The sections show irregular fragments of crushed brain lesion composed of astrocytic cells with atypical nuclei, many gemistocytes, foci of necrosis and mitotic figures. with regarding the submitted tissue that is crushed and small, making differential histologic diagnosis between anaplastic astrocytoma (gemistocyte rich) and glioblastoma multiform is very difficult.

Final diagnosis: High-grade glioma.

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