Methanol is a highly toxic substance, and a component of many household, industrial, and recreational use. Methanol toxicity is achieved by it's metabolism and eventual accumulation of formic acid. Neurological disability and prognosis of sequelae is often poor, and usually correlates with extent of structural brain involvement.

In this case, extensive signal abnormalities can be appreciated, consistent with reported widespread injury secondary to methanol intoxication, in the typical historical and clinical manifestations. This case presented emphasizes early radiographic changes indicating necrotic hemorrhagic complications of methanol ingestion.