Pulmonary cryptococcosis is an infection of the lungs caused by cryptococcus neoformans ^1-3. The radiologic findings of cryptococcal infection vary according to immune status ^3-7. The most common CT manifestations in immunocompetent individuals are multiple scattered or clustered nodules, solitary pulmonary nodule, as well as mass-like and consolidation ^3-7. Lymphadenopathy and pleural effusion may infrequently occur ^3-7.

The current case illustrates a presentation of an immunocompetent patient with histopathological proven pulmonary cryptococcosis and demonstrates the diagnostic challenge this infection poses to the radiologist.