Neurosarcoidosis

Case contributed by Gabriela Nicole Cepeda De Jesus
Diagnosis almost certain

Presentation

Left-sided headaches, nausea.

Patient Data

Age: 50 years
Gender: Female
mri
This study is a stack
Axial
FLAIR
This study is a stack
Axial
SWI
This study is a stack
Axial
T1
This study is a stack
Axial
T2
This study is a stack
Axial
ADC
This study is a stack
Axial
DWI
This study is a stack
Axial T1
C+ fat sat
This study is a stack
Axial
T1 C+
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Info

A T1-isointense and T2-hypointense enhancing dural-based, enhancing mass over the left sphenoid wing/middle cranial fossa measuring 4.3 x 4.5 x 5.0 cm. In the left aspect of the foramen magnum, there is a smaller 2.7 x 1.5 x 3 cm dural-based mass with similar signal characteristics and enhancement pattern.

Case Discussion

The patient underwent left pterional craniotomy for resection of the left sphenoid wing/middle cranial fossa dural-based mass. The final pathology demonstrated mass-forming sheets of epithelioid non-necrotizing granulomas, most consistent with sarcoidosis.

Upon further work-up, the patient did not have identifiable systemic sarcoidosis and was diagnosed with isolated neurosarcoidosis. Isolated neurosarcoidosis has been described in the literature as a rare occurrence (<1% of sarcoidosis cases).

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