PI-RADS 4 lesion

Case contributed by Lam Van Le
Diagnosis certain

Presentation

Ultrasound revealed an enlarged prostate. Blood tests showed elevated PSA levels (15.62ng/mL).

Patient Data

Age: 80 years
Gender: Male
mri
This study is a stack
Axial
T2
This study is a stack
Coronal
T2
This study is a stack
Sagittal
T2
This study is a stack
Axial DWI
b1400
This study is a stack
Axial
ADC
This study is a stack
Axial T1 C+ fat
sat Dynamic
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Info

The prostate is enlarged, measuring approximately 51 x 54 x 42 mm (width x height x anteroposterior), with an estimated volume of ~60 ml. PSA density 0.26 ng/ml.

In the right posterolateral peripheral zone at the midportion level, there is a poorly defined nodule with low signal intensity on T2W imaging (≤14 mm in diameter), high signal intensity on DWI (b = 1400), and marked hypointensity on ADC (indicating true diffusion restriction). The nodule demonstrates early contrast enhancement on dynamic T1FS +C imaging.

Normal seminal vesicles.  No pelvic nodes.  No bone lesions.

Case Discussion

Imaging findings are consistent with a PI-RADS 4 lesion in the peripheral zone of the prostate. The patient subsequently underwent a biopsy, and histopathological results confirmed prostate adenocarcinoma.

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