Tolosa-Hunt syndrome

Case contributed by Magdi Mahsoub
Diagnosis almost certain

Presentation

The patient complains of left orbital pain and squint.

Patient Data

Age: 20 years
Gender: Female
ct
This study is a stack
Axial
non-contrast
This study is a stack
Axial
non-contrast
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mri
This study is a stack
Axial
T1
This study is a stack
Axial
T2
This study is a stack
Axial
FLAIR
This study is a stack
Axial
DWI
This study is a stack
Axial
ADC
This study is a stack
Axial
SWI
This study is a stack
Sagittal
T1
This study is a stack
Coronal
T2
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The suspected area of abnormal density on CT at the left cavernous sinus and extends to the left orbital apex is more obvious on MRI and reveals isointense T1 signal, slight hypointense signal at T2 and FLAIR and causes mild attenuation of the cavernous left ICA and increases the distance between the lateral wall of the left cavernous sinus and ICA. Mild periarterial high T2/FLAIR signal is seen also on the left side.

Otherwise, unremarkable MRI brain and orbits.

6 hours later

ct
This study is a stack
Axial C+ portal
venous phase
This study is a stack
Axial C+ portal
venous phase
Axial C+
arterial phase
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CT with IV contrast confirms the filling defect in the left cavernous sinus which extends to the left orbital apex and revealed no appreciable enhancement could be seen.

Opacified with normal calibre superior ophthalmic vein (no thrombosis).

No carotid-cavernous fistula.

Case Discussion

The clinical data (ophthalmoplegia and squint, which is mostly due to abducent nerve involvement) and radiological findings suggest Tolosa-Hunt syndrome. After corticosteroid therapy, there was a dramatic improvement in the patient's symptoms.

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