This case represents left cerebral hemiatrophy in a young child with epilepsy. Cerebral hemiatrophy has a variety of causes and is generally associated with seizures and hemiplegia. Imaging features include thinning of the grey matter cortex, reduced volume of the underlying white matter, reduced myelination, enlargement of the lateral ventricle and reduced size of cerebral peduncle. The resultant reduction in cerebral volume, if early enough, can lead to changes in the skull, known as Dyke-Davidoff-Masson syndrome.
Differential diagnosis of similar brain morphology: