Pilocytic astrocytoma

Discussion:

This was histo-pathologically proven case of pilocytic astrocytoma (juvenile) with tumor cells showing GFAP positivity in their cytoplasmic processes.

Pilocytic astrocytomas represent the most common childhood brain tumor, frequently in the cerebellar region. This case shows a less common location in the optic pathway, which is seen in about 20% to 30% of cases. In this case it is a predominantly solid mass with minimal to no cyst-like component. No vasogenic edema is a valuable clue to diagnosis. Surgical resection is the treatment of choice with radiation and chemotherapy for optic and hypothalamic region tumors.

Differential, in this case, included suprasellar germinoma and craniopharyngioma.

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