Given the uveitis and involvement of the upper brainstem/basal ganglia, which disease could be responsible?
Behcet's disease.
Which parts of the body would you advise the referring clinician to examine?
Mouth and genital areas for ulcers.
What are the two most common neuro-radiological manifestations of this disorder?
1. Parenchymal involvement affecting the upper brainstem extending into the thalamus and basal ganglia. 2. Venous sinus thrombosis.
MRI shows high signal intensity around the posterior limb of the right internal capsule, extending superiorly into the centrum semiovale, and inferiorly into the cerebral peduncle. Similar changes are seen on the left side, but these are less prominent. No evidence of restricted diffusion. Following gadolinium administration, patchy foci of enhancement are seen around the right internal capsule.