The above described findings are consistent with Dyke-Davidoff-Masson syndrome (hemispheric infarction) with left cerebral hemiatrophy and fronto-parietal encephalomalacia, likely due to in-utero vascular insult.
The differential diagnosis includes:
Chronic Rasmussen encephalitis (chronic, progressive, unilateral inflammation of brain of uncertain etiology with hemispheric volume loss and intractable focal seizure activity ) however, Rasmussen encephalitis tends not to have calvarial changes.
Sturge-Weber syndrome
- progressive hemispheric atrophy and enhancement of pial angiomas
- cortical calcifications
- port-wine facial nevus (clinically)