Extra-abdominal desmoid fibromatosis

Discussion:

HISTOPATHOLOGY:

Parts of a fibroblastic spindle cell lesion without significant cellular atypia. In immunohistochemistry, strong nuclear staining for b-catenin in the majority of spindle cells with partial positivity for desmin and SMA.

In the PCR analysis of the CTNNB1 gene (Exon 3) detection of a point mutation (c.121A>G; p.T41A).

CONCLUSION:

Extra-abdominal desmoid fibromatosis.

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