The ostium of the ophthalmic artery has a sharp-angled take off from the C6 segment of the internal carotid artery (usually anteriorly). However, in some cases, it has an anterolateral take-off. After the ostium, the ophthalmic artery has a sharp upward-downward bend in a lateral direction to wrap around the anterior division. The catheters used are usually flowing direction catheters. However, detachable tip microcatheter can be used safely. The average inner diameter of the catheter is 1.0-1.5 Fr. It is important to engage the ostium and simulate the injection rate to verify the total flow of the drug into the ophthalmic artery with no reflux to the internal carotid artery.