This is a case of anti-Ma2/Ta-associated encephalitis, representing a form of paraneoplastic encephalitis.

Anti-Ma2/Ta-associated encephalitis may manifest as isolated or combined limbic, diencephalic or brainstem encephalitis. Typical clinical features include confusion and eye movement abnormalities. CSF analysis typically shows inflammatory changes. The most common underlying malignancy is testicular cancer, followed by lung cancer.

This patient's neurological symptoms improved significantly following treatment with intravenous methylprednisolone.