Imaging features are consistent with malignant pleural mesothelioma and subsequently confirmed on histology.
Pathological report:
Microscopic description:
Fragments of fibroconnective tissues are seen revealing focal aggregation of mesothelial cells at the surface of the specimen. There are also scattered foci of infiltrations of connective tissue by sheets of epithelial cells few of them have atypical angulated large nuclei.
Pathological diagnosis:
Atypical mesothelial proliferations.
IHC report:
The neoplastic cells express immunoreactivity as below:
Positive for
Calretinin (scattered)
CK 5/6 (scattered)
CKAE1/AE3 (scant)
CK7 (scant)
Ki 67 (30%)
Negative for
TTF1
Diagnosis:
IHC expression is consistent with malignant mesothelioma.