Secondary pulmonary lymphoma

Discussion:

Since the patient has a history of gastric non-Hodgkin lymphoma (mantle cell type) transbronchial biopsy was performed. It revealed signs of lymphagitic carcinomatosis of mantle cell lymphoma (anaplastic variant).

Location of primary tumor in stomach relatively commonly associated with pulmonary lymphagitic carcinomatosis1,2. Precise spectrum of risk factors is unknown, but in this case dramatic progression of the disease might be caused by using of immunosuppressive therapy (tocilizumab) and pathologic impact of the novel coronavirus (SARS CoV-2) itself.

Although no specific findings for lymphagitic carcinomatosis3,4, a high index of suspicion is required in any patient with a new lung abnormality, especially diffuse, and known non-Hodgkin lymphoma in the anamnesis1-4

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