Hypertrophic Olivary Degeneration (HOD) is a rare trans-synaptic neurodegenerative disorder caused by an injury within the Guillain-Mollaret Triangle (GMT) or Dento-Rubro-Olivary tract which is an anatomical-functional inhibitory loop 1. Damage to this pathway may cause oculopalatal myoclonus and upper limb tremors 2.
Familiarity with this entity is mandatory to avoid misinterpretation of the medullary lesion.
Case courtesy of Dr. Parisa Hajalioghli, Tabriz University of Medical Sciences, Iran.