Primary hepatic lymphoma - diffuse large B-cell lymphoma (DLBCL)

Discussion:

MRI features of a large lobulated hypoenhancing hepatic mass with very low ADC.

The patient underwent an ultrasound-guided biopsy, that confirms the diagnosis of a primary hepatic lymphoma (diffuse large B-cell lymphoma (DLBCL) in this case).

Primary hepatic lymphoma (PHL) is very rare, with approximately 100 described cases in the literature and accounts for <1% of all non-Hodgkin lymphomas.

it is primarily found in immunocompromised patients due to AIDS/HIVcongenital immunodeficiency, collagen vascular disease, and immunosuppressant therapy for organ transplant.

Diffuse large B-cell lymphoma is the most common histological subtype. Other histologic subtypes include:

Additional contributor: Dr. D Merazga, MD, Mezdaouet Clinic, Khenchela, Algeria

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