Tuberculous spondylitis or Pott disease is the most common musculoskeletal form of tuberculosis.
In the present case, the positive IGRA test for tuberculosis and the known history of a close relative with untreated respiratory tuberculosis are highly suspicious for tuberculous spondylitis.
Sometimes, however, the clinical history isn't so clear and laboratory exams are inconclusive. In such cases, it may be difficult to differentiate tuberculous vs pyogenic spondylitis.
Some findings that favor spinal tuberculosis are:
thoracic spine location
paravertebral abscess
abscess walls are thin and smooth
well-defined abscess margins postcontrast
multiple vertebrae involved
vertebral body destruction