What is the difference between multifocal and multicentric glioblastoma?
When there are multiple discrete areas of contrast-enhancing tumours without connecting T2/FLAIR signal abnormality, they are called as multicentric (considered as separate synchronous tumours), while if there are connecting T2/FLAIR signal abnormality between the enhancing lesions, they are called multifocal (considered as spread of tumor along white matter tracts).
There is an aggressive mass lesion centred on the splenium of corpus callosum extending to the left temporal lobe showing T1 low signal, T2 high signal, with peripheral irregular diffusion restriction and avid post-contrast enhancement, central necrosis and haemorrhagic changes.
Similarly featured lesion is also noted in the grey-white matter junction of the right frontal lobe.
There is perilesional oedema surrounding both lesions. No hydrocephalus. No infratentorial lesions.