WHO classification of odontogenic and maxillofacial bone tumors

Changed by Joachim Feger, 14 Aug 2021

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The WHO classification of odontogenic and maxillofacial bone tumours, last published in 2017, is a subset of the WHO classification of head and neck tumours (4^th edition), which lays out a histological classification system for neoplasms and other tumours related to the odontogenic apparatus.

Classification

Malignant odontogenic tumours

odontogenic carcinomas
- ameloblastic carcinoma
- primary intraosseous carcinoma, not otherwise specified
- sclerosing odontogenic carcinoma
- clear cell odontogenic carcinoma
- ghost cell odontogenic carcinoma
odontogenic carcinosarcoma
odontogenic sarcomas

Benign odontogenic tumours

benign epithelial odontogenic tumours
- ameloblastoma
  - ameloblastoma, unicystic type
  - ameloblastoma, extraosseous/peripheral type
  - metastasising ameloblastoma
- squamous odontogenic tumour
- calcifying epithelial odontogenic tumour
- adenomatoid odontogenic tumour
benign mixed epithelial and mesenchymal odontogenic tumours
- ameloblastic fibroma
- primordial odontogenic tumour
- odontoma
- dentinogenic ghost cell tumour
benign mesenchymal odontogenic tumours
- odontogenic fibroma
- odontogenic myxoma/myxofibroma
- cementoblastoma
- cemento -ossifying fibroma

Odontogenic cysts

odontogenic cysts of inflammatory origin
- radicular cyst
- inflammatory collateral cysts
odontogenic and non-odontogenic developmental cysts

Malignant maxillofacial bone and cartilage tumours

Benign maxillofacial bone and cartilage tumours

Fibro-osseous and osteochondromatous lesions

Giant cell lesions and simple bone cyst

Hematolymphoid tumours

solitary plasmacytoma of bone

~~-<li>primary intraosseous carcinoma, not otherwise specified</li>~~
+<li><a title="Primary intraosseous carcinoma, not otherwise specified" href="/articles/primary-intraosseous-carcinoma">primary intraosseous carcinoma, not otherwise specified</a></li>
~~-<li><a title="Glandular odontogenic cyst" href="/articles/glandular-odontogenic-cyst">glandular odontogenic cyst</a></li>~~
+<li><a href="/articles/glandular-odontogenic-cyst">glandular odontogenic cyst</a></li>

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