Chronic renal transplant rejection

Chronic renal transplant rejection is a form of renal transplant rejection. It usually later following transplantation.

Chronic rejection is defined as a gradual deterioration in graft function beginning at least 3 months after transplantation 3

The creatinine levels may rise but this does not allow differentiation from an acute transplant rejection.

Histological diagnosis is made demostration of graft arteries and arteriolar proliferation, interstitial cellular infiltration and fibrosis, tubular atrophy, and glomerular changes.

  • previous episodes of acute rejection

Imaging of choice. features include

  • mild dilatation of the collecting system: may occasionally be seen in cases of chronic rejection.
  • the cortex may be thin
  • narrowing at the ureterovesical junction
  • focal pyelonephritis
  • elevated renal arterial resistive indices
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Article information

rID: 41927
System: Urogenital
Synonyms or Alternate Spellings:
  • Chronic post transplant rejection - kidneys
  • Chronic post transplant rejection - kidney
  • Chronic kidney transplant rejection

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