Parasitic leiomyoma

Last revised by Henry Knipe on 7 Jan 2025

Parasitic leiomyomas/fibroids are extra-uterine leiomyomas that present as benign peritoneal pelvic or abdominal smooth-muscle masses separate from the uterus.

This leiomyoma likely originates as a pedunculated subserosal leiomyoma that twists and torses from its uterine pedicle. The contact with the uterus is then lost. Once free in the peritoneal cavity, it survives by recruiting neo-vascularization from adjacent structures. The originating pedunculated fibroid likely develops pre-menopausally, whereas the parasitic leiomyoma may become clinically evident before or after menopause ref.

This leiomyoma may also exist after surgery when small portions of the leiomyoma fall into the peritoneal cavity ref.

Occasionally, a broad ligament leiomyoma is also termed as a parasitic leiomyoma 4.

Parasitic leiomyomas are classified under the FIGO system as type 8 5.

On imaging, a parasitic leiomyoma presents as a solid pelvic or abdominal mass with characteristics similar to uterine leiomyoma ref

With behavior similar to uterine leiomyoma, a parasitic leiomyoma may recur after resection or, conversely, may show hormone-responsive behavior, including size stability or even shrinkage with natural, surgical, or chemical menopause ref

Surgery is usually performed for symptomatic relief or to prevent impingement of vital structures ref.

The differential for a parasitic leiomyoma varies with its location and includes ref:

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