Serpent sign
Last revised by Mohammad Salem Amer
on 30 Jun 2024
Citation, DOI, disclosures and article data
Citation:
Haouimi A, Amer M, Weerakkody Y, et al. Serpent sign. Reference article, Radiopaedia.org (Accessed on 21 Mar 2025) https://doi.org/10.53347/rID-67678
rID:
67678
Article created:
Disclosures:
At the time the article was created Ammar Haouimi had no recorded disclosures.
View Ammar Haouimi's current disclosures
Last revised:
30 Jun 2024,
Mohammad Salem Amer
Disclosures:
At the time the article was last revised Mohammad Salem Amer had no financial relationships to ineligible companies to disclose.
View Mohammad Salem Amer's current disclosures
Revisions:
7 times, by
7 contributors -
see full revision history and disclosures
Systems:
Sections:
Synonyms:
- Snake sign
- Serpent signs
- Snake signs
The serpent sign, (also knowns as the snake sign), is a sign described in hydatid disease. The WHO classification (2001) or Gharbi classification (1985) of hydatid disease describe several stages on ultrasound 1.
During the active stage, the cyst is composed of three layers: the outer (pericyst), the middle (ectocyst), and the inner (endocyst) 1. When the pressure increases within the cyst, there may be rupture with dissection of the ectocyst from the pericyst 1. This collapsed ectocyst, within an intact pericyst, can be visible on ultrasound as well as on CT and MRI and looks like a snake or serpent, hence the name 1.
References
- 1. Xiang H, Han J, Ridley WE, Ridley LJ. Snake or serpent sign: Hydatid. (2018) Journal of medical imaging and radiation oncology. 62 Suppl 1: 107. doi:10.1111/1754-9485.51_12784 - Pubmed
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