Citation, DOI, disclosures and article data
Citation:
Rozmiarek J, Weerakkody Y, Spindle cell rhabdomyosarcoma. Reference article, Radiopaedia.org (Accessed on 25 Feb 2025) https://doi.org/10.53347/rID-8327
Spindle cell rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma.
Epidemiology
There may be increased male predilection. May present at any age
Pathology
Histologically this tumor can resemble a leiomyosarcoma. It is composed mainly of fascicular, relatively monomorphic spindle-shaped cells that show unequivocal immunohistochemical and ultrastructural evidence of myogenic differentiation.
Location
There is predilection for the paratesticular region and the head and neck.
Treatment and prognosis
Compared to other rhabdomyosarcomas, it has a good prognosis 1.
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1. Imaging of Soft Tissue Tumors. F. Vanhoenacker (Editor), A.M. De Schepper (Editor), P.M. Parizel (Editor), J. Gielen (Editor). Springer ISBN:3540248099 (find it at amazon.com)
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2. Nascimento AF, Fletcher CD. Spindle cell rhabdomyosarcoma in adults. Am. J. Surg. Pathol. 2005;29 (8): 1106-13. Pubmed citation
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3. Rubin BP, Hasserjian RP, Singer S et-al. Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis. Am. J. Surg. Pathol. 1998;22 (4): 459-64. Pubmed citation
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4. Carroll SJ, Nodit L. Spindle cell rhabdomyosarcoma: a brief diagnostic review and differential diagnosis. Arch. Pathol. Lab. Med. 2013;137 (8): 1155-8. doi:10.5858/arpa.2012-0465-RS - Pubmed citation
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