It is an uncommon and challenging clinical condition when a molar pregnancy coexists with a live twin fetus. One in 20,000 to 100,000 births result in twins with a healthy fetus and hydatidiform mole.

An increased risk of severe pregnancy problems, including vaginal bleeding, preeclampsia, hyperthyroidism, intrauterine death, and gestational trophoblastic neoplasia, is linked to a hydatidiform mole with a live fetus.