Sclerosing angiomatoid nodular transformation of the spleen

Discussion:

An incidentally discovered splenic mass showed characteristic low signal intensity on T1 and T2WI, suggestive of sclerosing angiomatoid nodular transformation (SANT) of the spleen. In contrast, most of the differential diagnoses for splenic masses, such as splenic hemangioma or hamartoma, elicit high T2 signal, and splenic lymphoma elicits low to iso-intensity compared to the background parenchyma of the spleen. The increased prominence of low-signal-intensity foci on in-phase image is compatible with the presence of hemosiderin with numerous low-signal-intensity foci throughout the lesion in T2-weighted fat-saturated axial images. 

Stability of the size at the CT done two years after the MRI was in keeping with the benign nature of the mass confirming the diagnosis of SANT.

SANT often displays characteristic CT and MRI findings, including arterial or portal venous phase peripheral enhancing radiating lines, progressive enhancement, and hypointense T2 signal intensity. 

    Create a new playlist
Loading...