Adamantinomatous craniopharyngioma

Case contributed by Mustafa Takesh
Diagnosis almost certain

Presentation

Profound left optic neuropathy, to rule out a compressive lesion.

Patient Data

Age: 55 years
Gender: Male
This study is a stack
Axial C+
delayed
This study is a stack
Coronal C+
delayed
This study is a stack
Sagittal
C+ delayed
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Info

Selected CT images demonstrating a large suprasellar mass composed of cystic and enhancing solid components with scattered tiny calcifications. Significant mass effect on the brainstem and 3rd ventricle with encasement of the basilar artery. 

This study is a stack
Axial
T2
This study is a stack
Axial
FLAIR
This study is a stack
Axial
T1 C+
This study is a stack
Sagittal
T1 C+
This study is a stack
Axial
DWI
This study is a stack
Axial
ADC
This study is a stack
Sagittal
T1
This study is a stack
Sagittal
FLAIR
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Info

Selected MRI images showing a large suprasellar/hypothalamic mass with cystic and solid enhancing components, resulting in a  significant mass effect on the third ventricle, midbrain and the pons. There are also haemorrhagic components. 

postoperative MRI 2 wk later

mri
This study is a stack
Axial
T2
This study is a stack
Axial
FLAIR
This study is a stack
Axial
T1 C+
This study is a stack
Axial
T1
This study is a stack
Sagittal
T1
Download
Info

In the interval, a left frontotemporal craniectomy has been carried out with partial resection of the large, suprasellar mass lesion. There is a significant improvement of the mass effect.

Case Discussion

Classic MRI features of an adamantinomatous craniopharyngioma with multiple cysts, some of which are filled with blood products. There are also calcifications, which often occur in the adamantinomatous craniopharyngioma (in about 90% of cases).

In general, adamantinomatous craniopharyngiomas have a bimodal distribution with two peaks (between 5 and 15 years and over 40 years).

The histological report confirmed an adamantinomatous craniopharyngioma (WHO grade 1).

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