Corpus callosal dysgenesis with tubulonodular lipoma

Case contributed by Dalia Ibrahim
Diagnosis certain

Presentation

Seizures.

Patient Data

Age: 20 years
Gender: Male

Corpus callosum dysgenesis with a small callosal remnant. 

Large inter-hemispheric tubulonodular lipoma eliciting high signal on T1 and  T2 WI.  It extends via the choroidal fissures to involve both choroid plexuses of both lateral ventricles.

On MRS, there's a marked elevate lipid/lactate peaks.

The tubulonodular lipoma appears of low attenuation with a marginal rim of calcifications.

Case Discussion

Tubulonodular lipoma is usually associated with corpus callosum agenesis/dysgenesis. It frequently demonstrates calcifications. It also may extend into the lateral ventricles and the choroid plexus.

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