Corpus callosal dysgenesis with tubulonodular lipoma

Case contributed by Dalia Ibrahim
Diagnosis certain

Presentation

Seizures.

Patient Data

Age: 20 years
Gender: Male
This study is a stack
Sagittal
T2
This study is a stack
Axial
T2
This study is a stack
Axial
FLAIR
This study is a stack
Axial
DWI
This study is a stack
Axial
Gradient Echo
This study is a stack
Coronal
T1
This study is a stack
Axial
T1
This study is a stack
Axial
ADC
This study is a stack
Axial
T1 C+
This study is a stack
Coronal
T1 C+
MRS
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Info

Corpus callosum dysgenesis with a small callosal remnant. 

Large inter-hemispheric tubulonodular lipoma eliciting high signal on T1 and  T2 WI.  It extends via the choroidal fissures to involve both choroid plexuses of both lateral ventricles.

On MRS, there's a marked elevate lipid/lactate peaks.

This study is a stack
Axial
non-contrast
This study is a stack
Coronal
non-contrast
This study is a stack
Sagittal
non-contrast
Download
Info

The tubulonodular lipoma appears of low attenuation with a marginal rim of calcifications.

Case Discussion

Tubulonodular lipoma is usually associated with corpus callosum agenesis/dysgenesis. It frequently demonstrates calcifications. It also may extend into the lateral ventricles and the choroid plexus.

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