Cystic leukoencephalopathy without megalencephaly

Case contributed by Heba Abdelmonem
Diagnosis almost certain

Presentation

Delayed mental milestones. Normal head size. Recent onset of abnormal behaviors.

Patient Data

Age: 20 years
Gender: Male

Multiple areas of altered white matter signal (low in T1 and high in T2 and FLAIR images) is demonstrated in the bilateral corona radiata semiovale regions and subcortical region of both temporal lobes accompanied with bilateral symmetrical temporal lobe subcortical cysts.

Case Discussion

A young patient with a series of MRIs since the age of 8 years, all of them exhibit the same findings of abnormal white matter signal as well as temporal subcortical cysts. all of the findings are in keeping with Cystic leukoencephalopathy without megalencephaly

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